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31, 32 A 2 fold increase in levothyroxine substitution therapy at initiation of imatinib treatment is recommended, along with close monitoring of thyroid function buy generic cytotec pill Serum aldosterone concentrations did not differ significantly between the groups with different levels of albuminuria, but patients with heavy albuminuria showed a marked increase 5 fold in renal MR mRNA expression compared with patients with no or moderate albuminuria